Alzheimer's Research

First test worldwide for auto-antibodies against Amyloid peptides

The first test worldwide for the determination of serum auto-antibodies against Amyloid peptides is presented by DRG for the World Alzheimer´s Day 2011.
This test is part of a new product family, which supports the research in Alzheimer's disease.
The second test in this new product family is the Abeta-40 ELISA, for the detection of Amyloid β 1-40 peptides in serum, plasma and liquor:

Amyloid beta (1-40) (Human), EIA-5231

Amyloid beta Auto-Ab (Human) Serum, EIA-5099

Background information Alzheimer's disease:

Alzheimer's disease (AD) is characterized by the deposition of amyloid plaques, degeneration and loss of neurons, accumulation of fibrillary tangles in neurons, and a progressive loss of cognitive function.

Amyloid plaques are mainly composed of amyloid-beta (Aβ) 40 and 42 peptides derived from the proteolytic cleavage of amyloid precursor protein (APP).The concentration of Aβ peptides in serum and liquor depends on age and disease severity, and is further modulated by production of Aβ peptides in large peripheral organs, movement from brain interstitial fluid into blood stream, peripheral uptake and clearance of Aβ peptides in the liver and by naturally occurring auto-antibodies against Aβ peptides. This may explain why much of the plasma Aβ peptide data in cross-sectional studies does not show significant differences between sporadic AD and controls. In this respect, longitudinal studies seem more promising, showing initially elevated Aβ42 levels in those that eventually develop AD in the future.

Recent studies further indicate that the tendency of Aβ peptides to aggregate is greatly enhanced by the formation of reactive oxygen species by monoamine oxidase and the direct influence of nitric oxide synthase (NOS2).

As Aβ peptides are considered to play an early and pivotal role in AD pathogenesis, they may be a useful tool in diagnosing AD in the preclinical/early stages, as well as for monitoring potential Aβ peptide modifying therapies, since clearance of Aβ from the brain represents an important therapeutic strategy for prevention and treatment of AD.

Diagnostics that perform

Blutanalyse

News

30-Aug-2021 DRG can proudly announce:
The launch of Estriol total ELISA More...

25-Aug-2021 Diagnostics-4-Future
Meet DRG at this Conference at Lake Constance in October 2021 More...

15-Jun-2021 DRG Launches The New Software Version v2.70 For DRG:HYBRiD-XL
More...

19-Nov-2020 DRG newly developed SARS-CoV-2 (RBD) Antibody ELISAs:
IgG quantitative and Total Ab (IgA, IgM, IgG) More...

18-Nov-2020 DRG Intl, Inc. received MDSAP Certificate!
More...

16-Nov-2020 NEW high sensitive Estradiol ELISA for salivary samples
More...

19-Jun-2020 NEW: AMH (Anti-Mullerian Hormone) - fully automated - DRG:HYBRiD-XL
More...

18-Jun-2020 DRG proudly presents the launch of AMH ELISA
More...

24-Apr-2020 DRG awarded with a seal of approval "Innovativ Through Research"
More...

17-Feb-2020 NEW: Pancreatic Elastase (stool) - fully automated - DRG:HYBRiD-XL
More...

13-Jan-2020 DRG will participate at Labquality Days in Helsinki
Please visit us at booth C5! More...

10-Jan-2020 DRG will exhibit at MEDLAB in Dubai
More...

23-Nov-2019 DRG is proud to announce the win of a Trophy at JIB in Paris
1st category: Processes and Technological Advances for Biological Analysis with Hepcidin 25 (bioactive) on DRG:HYBRiD-XL. More...

05-Nov-2019 New assay for DRG:HYBRiD-XL:
Anti-tissue Transglutaminase & Anti-Deamidated Gliadin Peptide More...

14-Okt-2019 DRG will participate at MEDICA 2019
Meet us at booth 3/A69! More...

05-Jul-2019 Meet DRG at AACC 2019 in Anaheim
More...

14-Jun-2019 Salivary Hepcidin assay has been nominated
for SelectScience Scientists' Choice Awards for Best New Clinical Product of 2018! More...

03-May-2019 Meet DRG at EuroMedLab 2019
More...

02-May-2019 DRG will participate at the 8th Congress of the International BioIron Society in Heidelberg
More...

16-Apr-2019 Iron Metabolism - New ELISA launched: sTfR
soluble Transferrin Receptor ELISA More...

19-Mar-2019 First Salivary Assay for DRG:HYBRiD-XL launched: Cortisol
More...

06-Mar-2019 DRG Corticosterone ELISA
New application with rat and mouse! More...

11-Jan-2019 DRG will exhibit at MEDLAB Middle East 2019!
More...

13-Dec-2018 DRG is launching a NEW and UNIQUE assay:
Salivary Hepcidin ELISA More...

06-Nov-2018 Free T3 and Free T4 ELISA launched!
More...

18-Oct-2018 DRG @ MEDICA 2018 (Booth 3/A69)
Please meet us there! More...

03-Sep-2018 New Diabetes Kits launched:
Ultrasensitive Insulin & C-Peptide More...

16-Jul-2018 Salivary Hepcidin
Metabolomics Research - Special Feature More...

04-Jul-2018 Please meet DRG @ AACC 2018!
Chicago, Booth #3438 More...

15-Jun-2018 DRG´s Optimized Saliva ELISAs
showcased at AACC 2018 More...

27-Feb-2018 New tumor marker assay for DRG:HYBRiD-XL: PSA
More...

23-Feb-2018 NEW DRG ELISA: AMH
New ELISA for the determination of Anti-Mullerian Hormone More...

18-Dec-2017 DRG will exhibit at MEDLAB Middle East 2018!
More...

23-Nov-2017 DRG:HYBRiD-XL is featured in LABBook 2017
More...

09-Nov-2017 New assay for DRG:HYBRiD-XL: Tumor Marker CA72-4
More...

24-Oct-2017 Join DRG at MEDICA 2017
Hall 3 / A69 More...

12-Sep-2017 New Poster presented using DRG´s optimized Salivary Testosterone Kit
Learn more about the optimized features of this ELISA! More...

04-Aug-2017 New assays for DRG:HYBRiD-XL: Beta hCG and Free Estriol!
Launched at AACC 2017! More...

27-Jul-2017 Come meet us at AACC 2017!
San Diego, DRG Booth 5521 More...

21-Jul-2017 Optimized DRG ELISA: Salivary Estrone
Correlates perfectly with LC-MS/MS! More...

26-May-2017 Dr. Geacintov 1930-2017
We regret to inform that our President and Founder of the company, Dr. Cyril Geacintov, passed away on Tuesday, May 23 More...

23-May-2017 Meet DRG at EuroMedLab in Athens
Hope to see you at DRG´s booth # 24. More...

17-May-2017 New Posters published
at BioIron 2017 in Los Angeles, USA. More...

09-May-2017 Longer Shelf Life:
AFP, FSH, Insulin for DRG:HYBRiD-XL More...

10-Apr-2017 Posters published at MEDLAB Asia Pacific 2017
More...

28-Feb-2017 DRG will exhibit at MEDLAB Asia Pacific 2017 in Singapore!
Please visit our booth Q11. More...

17-Jan-2017 DRG will exhibit at MEDLAB Dubai 2017!
More...

21-Oct-2016 New publication:
TM-CA 72-4 ELISA a useful diagnostic tool for Ovarian Cancer! More...

12-Oct-2016 Join DRG at MEDICA 2016
Hall 3 / A69 More...

06-Sep-2016 DRG:HYBRiD-XL in Kyrgyzstan
Customer call at URF, DRG´s successful distributor! More...

17-Aug-2016 NEW DRG ELISA: Salivary Progesterone HS ELISA
Correlates perfectly with LC-MS/MS! More...

15-Aug-2016 DRG:HYBRiD-XL is online in LAB Book 2016!
More...

13-Jul-2016 Calprotectin: Completely automated on DRG:HYBRiD-XL!
More...

30-Jun-2016 Come meet us at AACC!
Philadelphia, August 02 - 04, 2016 - DRG Booth 3713 More...

01-Jun-2016 New DRG:HYBRiD-XL assay AFP is available!
More...

31-May-2016 DEQAS proficiency testing
25-OH Vitamin D (total) ELISA succesfully passed DEQAS testing! More...

30-May-2016 Hepcidin Harmonization Study:
New Paper accepted by Clinical Chemistry More...

25-May-2016 After-Show Report HOSPITALAR 2016
DRG presented DRG:HYBRiD-XL and new ELISAs More...

29-Apr-2016 DRG exhibits at HOSPITALAR 2016!
Meet us in Sao Paulo, Brazil, May 17-20! More...

31-Mar-2016 Meet DRG @ European Iron Club in Innsbruck
April 7-10, 2016 More...

12-Feb-2016 Award Ceremony of the German Design Award!
More...

10-Feb-2016 DRG will exhibit at MEDLAB Asia Pacific 2016 in Singapore!
Please visit our booth J 37! More...

05-Jan-2016 DRG`s Hepcidin 25 (bioactive) HS
Presented At ASH Annual Meeting in Orlando (USA), December. More...

21-Dec-2015 New assays for DRG:HYBRiD-XL: LH and Prolactin!
More...

14-Dec-2015 DRG exhibits at ARAB Health 2016!
Please visit our booth Z6 A19, Medlab section. More...

12-Nov-2015 NEW DHT-optimized ELISA
Improved assay for detection of 5α-Dihydrotestosterone! More...

28-Oct-2015 Unique assay for DRG:HYBRiD-XL:
Hepcidin 25 (bioactive) More...

26-Oct-2015 German Design Award 2016
DRG:HYBRiD-XL is chosen! More...

20-Oct-2015 Join DRG at MEDICA 2015
Booth Hall 3 / A69 More...

03-Sep-2015 New DRG:HYBRiD-XL assay Insulin is available!
More...

03-Aug-2015 German Design Award 2016
DRG:HYBRiD-XL is nominated! More...

24-Jun-2015 Come meet us at AACC
Atlanta July 28–30, 2015 - DRG Booth # 819 More...

27-May-2015 After-Show Report HOSPITALAR 2015
Successful participation at the show in Brasil! More...

31-Mar-2015 NEW ELISA
DRG announces Hepcidin 25 (bioactive) HS ELISA. More...

27-Feb-2015 CRP-HS:
New clinical chemistry parameter now available for DRG:HYBRiD-XL! More...

06-Feb-2015 DRG Events 2015
Our list of events is online now! More...

27-Jan-2015 Press release:
Martina Werner, Member of the European Parliament, visited DRG! More...

12-Jan-2015 HEPCIDIN
New paper published in "American Society of Hematology". More...

08-Jan-2015 DRG will exhibit at ARAB HEALTH 2015!
More...

29-Nov-2014 DRG @ ASH Annual Meeting 2014 in San Franscisco
More...

28-Nov-2014 New DRG:HYBRiD-XL assays DHEA and DHEA-S are available!
More...

06-Nov-2014 D-dimer for DRG:HYBRiD-XL available now!
More...

24-Oct-2014 MEDICA 2014
DRG will exhibit at MEDICA in same booth location Hall 3 A69. Please book your meeting with us More...

17-Oct-2014 New DRG:HYBRiD-XL assays TSH and free T4 are available!
More...

08-Oct-2014 DRG:HYBRiD-XL NEWS
Free Testosterone for DRG:HYBRiD-XL available now! More...

20-Aug-2014 HbA1c for DRG:HYBRiD-XL available now!
More...

17-Jul-2014 Cystatin C
New clinical chemistry parameter now available for DRG:HYBRiD-XL! More...

01-Jul-2014 Join DRG at AACC 2014!
Visit our booth at McCormick Place - Chicago, IL - Booth # 2431 More...

17-Jun-2014 DRG:HYBRiD-XL NEWS:
Androstenedione for DRG:HYBRiD-XL available now! More...

13-Jun-2014 DRG Winner of MDEA 2014 Award
DRG:HYBRiD-XL has been selected as the Bronze Winner of MDEA 2014! More...

27-May-2014 After-Show Report HOSPITALAR 2014
DRG presented DRG:HYBRiD-XL and new assays at HOSPITALAR More...

26-May-2014 New DRG:HYBRiD-XL Parameters available!
T3, T4 and free T3 are now available for purchase. More...

12-May-2014 DRG Events May 2014
Visit DRG booth at HOSPITALAR and House-of-Pharma More...

09-May-2014 DRG:HYBRiD-XL Finalist in MDE Awards
Our fully automated analyzer DRG:HYBRiD-XL is Honored as Finalist in the Medical Design Excellence Awards 2014. More...

30-Apr-2014 ECE 2014
DRG exhibits at the 16th European Congress of Endocrinology in Wroclaw, Poland and offeres live demos! More...

28-Mar-2014 Arab Health 2014 - Post Show Report
The Arab Health Exhibition is growing from year to year... More...

14-Feb-2014 DRG Events 2014
Our list of events in 2014 is online now! More...

09-Jan-2014 ARAB HEALTH 2014
DRG will exhibit at ARAB HEALTH in Dubai. Please book your meeting with us. More...

02-Dec-2013 DRG:HYBRiD-XL Testpanel launch
DRG has launched the first assays for DRG:HYBRiD-XL More...

28-Nov-2013 DRG launched 2 new movies at MEDICA
Check it out! More...

14-Oct-2013 MEDICA 2013
DRG will exhibit at MEDICA in same booth location Hall 3 A69. Please book your meeting with us More...

09-Aug-2013 After-Show Report SMTLSA
DRG and Biocom Diagnostics succesfully presented the Combi-Stand at SMTLSA 2013 More...

23-Jul-2013 New DRG flyer online
DRG has published the new broshure about Iron Metabolism and DRG Hepcidin ELISA! More...

05-Jul-2013 Exhibitions in July / August 2013
DRG will have a booth at AACC and SMTLSA More...

31-May-2013 CTGF ELISA biomarker for chronic liver diseases!
A new study has shown that DRG CTGF ELISA might be a helpful non-invasive tool for monitoring chronic liver diseases. More...

29-Apr-2013 Grand Opening Ceremony
DRG International Celebrates Opening of the New Corporate Headquarters More...

05-Apr-2013 Exhibitions in April / May 2013
Visit DRG booth at ECCMID, EUROMEDLAB or HOSPITALAR More...

22-Mar-2013 DRG @ CACLP 2013
DRG Group successfully showcased at the CACLP 2013 in Xi'an, China More...

08-Mar-2013 Chlamydia and TORCH ELISAs CE certified!
DRG obtained the CE mark for 10 Infectious Diseases ELISAs! More...

05-Mar-2013 DRG`s Progesterone and Cortisol ELISAs successfully used on wild whales and seals in Scotland
Results will be presented on Conference in Portugal More...

07-Feb-2013 DRG Group at ARAB HEALTH 2013
DRG participated at one of the world´s largest medical congress: Arab Health in Dubai More...

06-Dec-2012 More new DRG flyer online
DRG has published the new broshure about Aldosterone! More...

28-Nov-2012 New DRG flyer online
DRG has published the new broshure about 25-OH-Vitamin D! More...

02-Nov-2012 MEDICA 2012
DRG will present a spectacular media show! More...

31-Oct-2012 New DRG flyer online
DRG has published the new broshure about Alzheimer research! More...

15-Oct-2012 DRG:HYBRiD-XL
Showcased at 2012 "Pharmed and Healthcare Vietnam" More...

20-Sep-2012 DRG:HYBRiD-XL® CE-marked!
DRG can declare that the fully automated analyzer fulfills standards for CE regulations! More...

22-Jun-2012 AACC 2012
DRG exhibits again at the AACC Clinical Lab Expo and offeres live demos and a poster session! More...

15-Jun-2012 DRG & VDGH
New image brochure of VDGH shows DRG: HYBRID-XL in a visually stunning scene! More...

25-May-2012 After-Show Report HOSPITALAR
DRG and Biomedix succesfully presented the Combi-Stand at Hospitalar 2012 More...

11-May-2012 HOSPITALAR 2012
DRG is launching DRG:HYBRiD-XL to Latin America at HOSPITALAR in Sao Paulo, Brazil
More...

05-Mar-2012 DRG at MEDICAL FAIR INDIA 2012
DRG exhibited at MEDICAL FAIR INDIA in cooperation with authorized distributor Weldon Biotech More...

09-Jan-2012 ARAB HEALTH 2012
DRG will exhibit at ARAB HEALTH 2012 in Dubai. Please book your meeting with us More...

07-Nov-2011 MEDICA 2011
DRG will exhibit at MEDICA in same booth location Hall 3 A69. Please book your meeting with us. More...

21-Sep-2011 Alzheimer's Research
The first test worldwide for the determination of serum auto-antibodies against Amyloid peptides is presented by DRG More...

03-Sep-2011 New DRG Building officially dedicated!
The official dedication of the new addition to the DRG building took place on September 2nd in Marburg. More...

29-Jun-2011 AACC 2011
DRG International Inc. exhibits again at the AACC Clinical Lab Expo 2011 and will also present a poster in new fields of research. More...

23-May-2011 Medal of Honor
Cyril Geacintov, President and CEO of DRG Intl. awarded the Ellis Island Medal of Honor for his achievements as a business leader of diverse ethnic origin. More...

14-Apr-2011 New certificate for DRG list B products available!
DRG has successfully passed this years surveillance audit (TUV Rheinland) and has extended the list of CE approved List B products. We are proud to present the new certificate. More...

19-Jan-2011 AEO Certification:
In January 2011 DRG has obtained AEO status from the chief customs office in Giessen! More...

29-Dec-2010 NEW: DRG Movie MEDICA 2010
DRG presented at MEDICA 2010 a new and innovative booth design. Watch our new MEDICA movie! More...

13-Oct-2010 The Cornerstone Of The New DRG Building Addition In Marburg
The DRG Group is pleased to announce that the cornerstone of the new DRG building addition in Marburg was set in place More...

11-Oct-2010 DRG Acquires DIMA Diagnostica from bioMérieux
DRG Instruments will acquire the microtiter plate Elisa production, including existing finished stock, raw materials, from DIMA, which is based in Germany. More...

11-Aug-2010 DRG Renin-ELISA -
The worldwide first Sandwich-ELISA for the non-radioactive quantification of active Renin
In the United States, one third of the American adults have high blood pressure or hypertension, and among those, almost one third even do not know that they had the condition. More...

21-Jul-2010 DRG to launch DRG:Hybrid-XL at AACC
DRG offers Preview of major new fully-automated immunodiagnostic and clinical chemistry automatic reader. More...

01-Apr-2010 New article about the DRG Prolactin Elisa used in Angora goat plasma
DRG International, Inc. announces that researchers used the DRG Prolactin Elisa kit... More...

23-Dec-2009 DRG presented DRG:HYBRiD-XL at MEDICA 2009
Unique, fully-automatic, random access analyzer for immunoassays and clinical chemistry to be available for use in 2011. More...

24-Aug-09 WORLD'S FIRST HEPCIDIN TESTING KIT NOW AVAILABLE !
Test kit helps quickly diagnose iron disorders, including hemochromatosis and anemia. More...

Seal of approval

Seal of approval

Certificate

Certificate

EN-ISO-13485-2016 DE
EN-ISO-13485-2016 EN
Liste B Produkte DE
List B Products EN
AEO Zertifikat

© DRG INSTRUMENTS GMBH, DEUTSCHLAND

DATA PROTECTION | IMPRINT | CONTACT