Calprotectin completely automated on DRG:HYBRiD-XL^®

DRG is pround to announce the launch of Calprotectin (Stool) for DRG:HYBRiD-XL^®.

The new assay include 40 tests and has an incubation time of 60 min in total. You may order with the following catalog number: HYE-5767.

Clear advantages:

• Short assay time
• Broad assay range(up to 1500 µg/g)
• High sensitivity
• Completely automated
• Clinical significance of results highly comparable with market leaders
• Easy, fast and clean fecal sample handling (without manual dilution or pipetting)
• Two controls included and ready to use
• Two re-calibrators included and ready to use
• Random access

Clinical Utility:

Fecal Calprotectin is mainly used as non-invasive inflammation marker for diagnosis and therapy monitoring of inflammatory bowel diseases (IBD). Some other areas of application are:

• Differentiation of IBS (irritable bowel syndrome) and IBD to avoid unnecessary colonoscopy
• Assessment of inflammatory activity in Morbus Crohn and ulcerative colitis patients
• Differential diagnosis of chronic diarrhea to discriminate between an organic and a functional diarrhea

Reference Ranges:

• Negative < 50 µg/g
  NO inflammation in the gastrointestinal tract - No need of invasive procedures (colonoscopy)
• Grey Zone 50 - 200 µg/g
  Can represent mild organic disease - Repeat the measurement and perform further investigations
• Positive > 200 µg/g
  ACTIVE organic disease with inflammation in the gastrointestinal tract - Further investigation and curative procedures

Assay Characteristics:

• Assay Principle: Sandwich ELISA
• Sample Type: Fecal Extract
• Sample Handling: Fecal Extraction System
• Sample Volume: 6µl (+ 60µL dead volume)
• Dynamic Range: 7 - 1,500 µg/g
• Sensitivity: 7.0 µg/g (LoD)
• Total Assay Time: 1 hour (30/30 min)

Dedicated DRG Fecal Extraction System (FES):

Device for comfortable and fast extraction of stool samples!

Hygienic stool sample preparation system can be performed with the dedicated DRG Fecal Extraction System (FES). It is the device for comfortable, fast and hygienic extraction of stool samples. DRG catalog number is HYI-5989. One box contains of 100 extraction tubes, each filled with Extraction Buffer (ready to use).

The DRG Fecal Extraction System (FES) greatly simplifies the laborious procedure for stool preparation and is adapted to use on the DRG:HYBRID-XL^®. No additional manual dilution or pipetting steps are required. The stool sample tube can be put on the analyzer and the sample will be processed automatically.