Salivary Hepcidin ELISA: NEW and UNIQUE assay launched by DRG!
DRG is proud to announce the launch of a NEW and UNIQUE assay kit of DRG´s Iron Panel: Salivary Hepcidin (SLV-6082).
The hormone hepcidin plays an important role in regulating iron metabolism. It is a major regulator of dietary iron absorption and iron distribution in the body. In serum, the bioactive peptide hepcidin-25 has shown to be a useful biomarker for diagnosis of various specific disease conditions:
Hepcidin synthesis decreases under conditions of increased demand for circulating iron like
- Iron deficiency
- Hypoxia
- Anemia and
- Erythropoiesis.
In contrast, hepcidin synthesis is induced by inflammation, infection and iron overload.
Besides its presence in serum, Hepcidin-25 was additionally confirmed to be present in human saliva. Determination of Hepcidin-25 in saliva has the advantage of a non-invasive and stress-free sample collection without the need of medical personnel.
Specifications of the new assay kit Salivary Hepcidin, SLV-6082:
- Principle of the Assay: ELISA based on the principle of competitive binding
- Assay Range: 68.4 - 8,000 pg/mL
- Reagents: Ready to use, except Calibrators, Controls and Wash Buffer
- Sample Volume: 100 µL Saliva
- Incubation Time: 60/30/15 min at room temperature (no shaker needed)
- Mean reproducibility: Intra Assay 5.5 % CV; Inter Assay 10.7 % CV; Inter-Lot 5.8 % CV
