FIRST ELISA WORLDWIDE FOR THE DETERMINATION OF CMV IGG FROM BUCCAL SWAB SAMPLES
The DRG CMV IgG Buccal Swab ELISA is used for the quantitative and qualitative detection of IgG antibodies against Cytomegalovirus (CMV) in human buccal swab samples. (For Research Use Only. Not for use in diagnostic procedure.)
Buccal swabs are a non-invasive alternative to plasma-based CMV monitoring for non-diagnostic purposes such as donor screening for transplantation or population studies.
BACKGROUND INFORMATION
The cytomegalovirus (CMV) belongs to the human herpes viruses (human herpes virus 5). CMV is widespread worldwide and is considered the most common viral pathogen of congenital infection. Seroprevalence is dependent on age and socioeconomic factors of the population under study.[1] CMV is used in prenatal diagnostics as part of TORCH serology, but CMV status also plays a major role in transplant medicine. In transplantation, the aim is for the donor to have the same CMV status as the patient. If the patient is CMV-negative, the donor should also be so that the patient is not reinfected with CMV. If, on the other hand, he is positive, the donor should also be positive, because the donor‘s immune system is then already CMV-experienced and trained accordingly.[2] Whereas in the past CMV IgG could only be detected in blood, DRG has already been offering a CMV IgG ELISA for buccal swabs since 2018.
BENEFITS
Easy collection - Sampling without the need for trained health professional
Non-invasive and painless with buccal swabs
Convenient - Sampling can be done at donor´s home
Very good correlation to the blood test
Reliable results
No hidden cost - Can be processed on standard ELISA instruments (SLV-6110)
ASSAY CHARACTERISTICS
Assay Range: 0 – 80 DU/mL
Incubation Times: 60 / 30 / 10 min
Sample: Buccal Swab (Swabs not included in kit)
Controls: Negative and Positive Control included in Kit
Standards: 3 Standards 1-3 (Neg. Control is used as 0-Standard)
Processing: Manual or automated possible (protocols available for DYNEX DS2 and DSX)
No cross reactivity for Herpes-simplex Virus 1 and 2, Varicella zoster Virus and Epstein-Barr Virus (VCA)
ORDERING INFORMATION
Available in single kit version (SLV-6110) and as 300 plate kit (SLV-6084).
References [1], [2]: Please refer to product marketing brochure.
